Hyper­plasia of the endometrium

This term describes a benign thick­en­ing (hyper­plasia) of the lining of the uterus (endo­met­ri­um). Possible symptoms are altered uterine bleeding (heavier than normal menstrual bleeding, bleeding between actual periods or bleeding after menopause).

Endo­metri­al hyper­plasia is not a cancer of the uterine lining, it is rather con­sidered a precan­cer­ous stage. Despite the fact that treatment is usually limited to med­ic­a­tion (pro­ges­to­gens), scraping of the endo­met­ri­um and regular check-ups (none is harmful to the germ cells), proper coun­selling should still be sought regarding the future planning of a pregnancy. This is mainly relevant because of potential delay in con­cep­tion due to the necessary treatment which may lead to a reduction in fertility over time.


Endo­metri­al carcinoma

The endo­metri­al carcinoma describes a malignant change in the lining of the uterus.
Chemo­ther­apy is not necessary in the early stages. Current data on endo­metri­al carcinoma and the risk of uterine pre­ser­va­tion in women with an urgent desire to have children are limited. The assess­ment of fertility pre­ser­va­tion in endo­metri­al cancer requires an indi­vidu­al coun­selling and decision-making.
One way to facil­it­ate the patient’s decision after the con­sulta­tion regarding fertility pre­ser­va­tion measures is the “Decision Aid” linked here.

It is a digital aid for decision-making developed by psy­cho­lo­gists, psy­cho­ther­ap­ists and repro­duct­ive physicians.
One way to facil­it­ate the patient’s decision after the con­sulta­tion regarding fertility-pre­serving measures is the  “Decision Aid” linked here. This digital decision aid has been developed by psy­cho­lo­gists, psy­cho­ther­ap­ists and repro­duct­ive phys­i­cians and might help in an indi­vidu­al situation.

Detailed inform­a­tion and a bib­li­o­graphy can be found in the Fer­ti­PRO­TEKT booklet “Indika­tion und Durch­führung fer­til­ität­s­pro­tekt­iver Maßnahmen bei onko­lo­gis­chen und nicht-onko­lo­gis­chen Erkrankun­gen”, 2nd revised edition 2020, which was written by members of the Fer­ti­PRO­TEKT Netzwerk e.V. and is available free of charge (in German).

(Chap. 2.6)

An english version can be bought: Fertility Pre­ser­va­tion in Onco­lo­gic­al and Non-Onco­lo­gic­al Diseases a practical guide by Michael von Wolff & Frank Nawroth ISBN 978–3‑030–47567‑3 from Springer.com
Part II.VI page 85 ff