The removal of ovarian tissue for freezing (cryopreservation) for a later transplantation of the ovarian tissue in the case of a desire for children and a premature loss of ovarian function is an established and standardized reproductive medical technique. The method is recommended for young women of fertile age who have a direct or indirect risk of loss of ovarian function due to an oncological, haematological or other underlying disease. In addition, young girls for whom stimulation and egg freezing are not possible treatment options ovarian tissue cryopreservation should be considered.
A temporary restoration of the body’s own female hormone production with spontaneous pregnancies is one of the aims of this method. A major advantage of this technique is the short time required for the retrieval of ovarian tissue, as no hormonal preparation (stimulation) of the patient is necessary and the tissue can be retrieved at any time during the menstrual cycle. For the removal itself, the rule is: as much as necessary, as little as possible. Mostly, half an ovary is removed by laparoscopy, processed and frozen. It has been proven that pregnancies can be achieved even with a small amount of tissue without relevantly reducing the woman’s chance for a later spontaneous pregnancy (without transplantation).